Nutrigenomics: What It Is and How SNP Nucleotides Define the Nutrigenetic Profile
Nuria de Frutos / 2 March 2026
Nutrigenomics: What It Is and How SNP Nucleotides Define the Nutrigenetic Profile
How can genetic data be integrated into dietary practice? In this article, we explain what nutrigenomics is and show how nucleoids make it possible to define a solid nutrigenetic profile. Based on this foundation, we propose an approach to translate genetic information into personalised recommendations aligned with the principles of precision nutrition.
Nutrigenomics: what it is
Nutrigenomics studies how nutrients and bioactive compounds modulate gene expression and metabolic pathways. Its objective is to translate this diet–gene interaction into personalised and measurable dietary recommendations.
Differences between nutrigenomics and nutrigenetics
Nutrigenomics: how diet influences the expression of genes and biological pathways.
Nutrigenetics: how genetic variants (e.g., SNP nucleotide) determine the individual response to nutrients.
Both disciplines are complementary: nutrigenetics identifies susceptibility (which variants the person has), and nutrigenomics helps modulate the response through dietary and lifestyle changes.
Nutrigenomics testing
A rigorous approach usually includes:
A panel of SNP nucleotide with scientific support (folate/B12 methylation, vitamin D metabolism, lipids, caffeine/lactose, inflammation, antioxidants, detoxification).
Evidence-based interpretation: effect size, study quality/replication, possible interaction with microbiota and lifestyle, and level of recommendation. Reviews highlight that, despite the volume of associations, clinical translation requires caution, independent validation and follow-up of clinical endpoints.
SNP nucleotide: How to establish a nutrigenetic profile
Panel selection: prioritise SNPs with clinical utility and replicated evidence in the target of interest (e.g., lipids, blood pressure, vitamin metabolism).
Sampling and genotyping: saliva/blood, quality control and coverage; document technical limitations.
Multi-source integration: combine genotype with biomarkers (e.g., 25(OH)D, lipid profile), dietary records and lifestyle factors; where appropriate, consider microbiota/metabolomics.
Practical translation: adjust macros (quality of fats and carbohydrates), micronutrients (active forms and doses), bioactives (e.g., polyphenols, caffeine according to metabolisation) and behaviours (sleep, activity) that modulate pathways affected by SNPs.
Follow-up and re-evaluation: define indicators (biomarkers and clinical outcomes) and review the plan in response to changes in goals or new evidence.
Importance in precision nutrition
Precision nutrition seeks to define personalised dietary strategies to correct metabolic imbalances and improve quality of life, integrating knowledge of the intestinal microbiome, microbiota function and each person’s genetic information. This approach makes it possible to understand, with greater granularity, how diet impacts the body and to design guidelines tailored to the individual, rather than average recommendations.
The integration of nutrigenomics and SNP makes it possible to move from general recommendations to targeted and measurable interventions. These are some of the benefits:
Greater clinical response: prioritisation of targets (methylation, inflammation, lipids) with fine adjustments.
Personalised prevention: early detection of susceptibilities and protective dietary modifications.
Clear risk communication: reports with understandable language, limits and realistic expectations
In practice, precision nutrition integrates multiple dimensions of the individual (lifestyle, genetics, microbiota, metabolic response) to select targets and measure outcomes objectively, which strengthens clinical translation and adherence to the plan.
Calle Benjamín Franklin, 5 a 11, CP 46980 Paterna (Valencia)
Purpose
To attend to, register and contact you to resolve the request you make to us through this contact form
Legitimation
Your data will be processed only with your consent, by checking the box shown on this form
Recipients
Your data will not be transferred to third parties.
Rights
You have the right to request access to, correct or delete your data. You can also request that we limit its processing, oppose it and request the portability of your data by contacting our postal address or [email protected]
If you have any questions about how we will treat your data or would like to make any suggestions or complaints, please contact the Data Protection Officer at [email protected] or at the Data subject support form
I consent to the use of my personal data to process my request, as set forth in your Privacy Policy
I consent to the use of my data to receive information and commercial communications from your entity.
Nuria de Frutos
Biotecnología Industrial
Suscríbete a nuestra newsletter
Mantente al día de lo más destacado sobre innovación y nuevas tecnologías.
Gestionar el consentimiento de las cookies
We use our own and third-party cookies that provide us with statistical data and user browsing habits. This helps us improve our content and services, and even show advertising related to user preferences. You can activate these cookies by clicking the “Accept cookies” button. If you prefer to keep these cookies disabled, click the “Reject cookies” button. You can even activate and deactivate the ones you prefer by clicking the “Customize cookies” button. More information in our Cookies Policy
Técnicas
Always active
El almacenamiento o acceso técnico es estrictamente necesario para el propósito legítimo de permitir el uso de un servicio específico explícitamente solicitado por el abonado o usuario, o con el único propósito de llevar a cabo la transmisión de una comunicación a través de una red de comunicaciones electrónicas.
Preferencias
El almacenamiento o acceso técnico es necesario para la finalidad legítima de almacenar preferencias no solicitadas por el abonado o usuario.
Estadísticas
El almacenamiento o acceso técnico que es utilizado exclusivamente con fines estadísticos.El almacenamiento o acceso técnico que se utiliza exclusivamente con fines estadísticos anónimos. Sin un requerimiento, el cumplimiento voluntario por parte de tu proveedor de servicios de Internet, o los registros adicionales de un tercero, la información almacenada o recuperada sólo para este propósito no se puede utilizar para identificarte.
Marketing
El almacenamiento o acceso técnico es necesario para crear perfiles de usuario para enviar publicidad, o para rastrear al usuario en una web o en varias web con fines de marketing similares.
