NIAS laboratorio

Identification, toxicological risk assessment and control of NIAS (Non-Intentionally Added Substances) to ensure food safety and regulatory compliance of packaging materials.

NIAS are chemical substances present in materials and packaging that are not intentionally added, but may be generated during manufacturing, processing, recycling or through material component degradation. Their presence represents one of the main current challenges in food safety and packaging, particularly in a context of new materials, recycled content and increasing regulatory requirements.

At AINIA, we support companies in identifying, interpreting and managing NIAS through advanced analytical testing, toxicological risk assessment and technical–regulatory advice, ensuring that food contact materials are safe, compliant and suitable for their intended use.

Why is it critical to address NIAS?

Food safety

NIAS may migrate from packaging into food, generating toxicological risks if they are not properly identified and controlled. Their analysis is essential to prevent emerging risks and protect consumers.

Regulatory compliance

European legislation requires that food contact materials do not transfer hazardous substances or alter food composition:
  • Regulation (EC) No 1935/2004
  • Regulation (EU) No 10/2011
  • New Declaration of Compliance (Regulation (EU) 2025/351), which reinforces information requirements on NIAS.
The identification and assessment of NIAS is key to demonstrating legal compliance to customers and authorities.

Material and process optimisation

NIAS analysis makes it possible to determine their origin (raw materials, additives, inks, adhesives, thermal processes or recycling) and to define corrective measures in formulation and manufacturing in order to minimise their presence at source.
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Our NIAS analysis service

At AINIA, we provide a comprehensive NIAS analysis, identification and interpretation service, tailored to the intended use of the packaging and the applicable regulatory framework.

Advanced analytical methodology

NIAS analysis is carried out using:
  • Gas chromatography (GC)
  • Liquid chromatography (HPLC)
  • High-resolution mass spectrometry
These techniques enable non-targeted detection, identification and semi-quantification of NIAS present in the material. Check the scope of accreditation at: AINIA laboratory ENAC accreditations
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Migración

What does the service include?

  • Detection and identification of NIAS in materials and packaging.
  • Expert interpretation of results.
  • Risk assessment.
  • Assessment of material suitability for its intended use.
  • Technical recommendations and corrective measures to minimise NIAS at source.

Risk assessment and regulatory support

Beyond chemical analysis, AINIA provides a differentiated approach:
· Toxicological assessment based on scientific and regulatory criteria.
· Exposure assessment.
· Support for the Declaration of Compliance.

Our team combines analytical expertise, food contact materials legislation and industrial experience, transforming analytical results into practical and safe decisions.

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Técnicos laboratorio

Who is this service for?

This service is particularly aimed at:
  • Manufacturers of packaging and packaging materials
  • Food companies using complex or innovative packaging
  • Processors of plastics, paper/cardboard and multilayer materials
  • Companies incorporating recycled materials
  • Departments of quality, R&D, regulatory affairs and packaging
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AINIA Packaging 360

Integration with AINIA Packaging 360

NIAS analysis is part of the AINIA Packaging 360 approach, enabling an integrated assessment of packaging safety, functionality, sustainability and regulatory compliance, from design to market.

Why AINIA?

  • Laboratories with advanced analytical technologies
  • Proven expertise in food contact materials
  • Integrated approach: analysis + risk + regulation
  • Personalised technical support
  • A vision focused on safe innovation in packaging
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How can I help you?

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Mónica Leal
Materials and Packaging Technology