AINIA / AVI – NANOBAC

AVI – NANOBAC

Production of small antibody formats in yeasts against different bacteria in the livestock sector (NANOBAC)

23 July, 2021

Objective

The

main objective

of NANOBAC is the creation of a reduced-format antibody library based on VHHs (Variable heavy of Heavy chain antibody), the smallest format of existing functional antibodies, as a tool to increase food safety with two possible applications for industry: food additives and a portable sensor for the early detection of foodborne pathogens.

Activities

Detection and production/isolation of membrane proteins from microorganisms for affinity screening.
Obtaining VHH collections through affinity screening.
Design of antibody formats based on high-affinity VHH sequences.
Recombinant production of antibodies for the development of the collection.
Experimental sensitivity tests of the antibodies in the collection.

Dissemination/Transfer

Project launch poster

AVI_NANOBAC_2021

Press releases

AINIA obtains €1.1 million from AVI to promote 6 R&D&I projects

Dissemination articles:

Reduced-format antibody library: a tool to increase safety in the livestock sector

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Valencia Technology Park c/ Benjamin Franklin, 5-11
E46980 Paterna (Valencia)

Tel. 96 136 60 90

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