- Beauty, health and wellbeing
Studies of health effects using in vitro cell models
Advanced assessment of health effects using 2D and 3D cell models
Market need
Food, nutritional supplement and cosmetics companies need to demonstrate the efficacy and functional safety of their ingredients and products in a robust and rigorous manner before launching them on the market.
The growing demand for scientific evidence from consumers, customers and regulatory bodies makes it essential to have reliable, reproducible and physiologically relevant experimental models that enable the assessment of mechanisms of action and health benefits at early stages of development.
Our solution
- In vitro preclinical studies based on advanced cell models to assess the biological effect of ingredients, extracts, formulations and final products.
- Extensive experience in 2D and 3D cell models, adapted to the specific needs of each project.
- Physiologically relevant models for the study of:
- Gut health.
- Metabolic and energy processes.
- Skin health.
- Muscle and bone health.
- Liver function.
- Characterisation of mechanisms of action to understand how ingredients and products work.
- Demonstration of functional efficacy using cell models adapted to each application.
- Generation of robust scientific evidence to support the development and validation of ingredients and products.
Applications
- Assessment of effects on gut health and barrier function.
- Studies of compound absorption and intestinal epithelial transport.
- Assessment of anti-inflammatory, antioxidant and immunomodulatory effects.
- Studies on energy metabolism and metabolic health.
- Assessment of satiety and lipid accumulation.
- Functional assays in liver, muscle and bone models.
- Analysis of cellular biomarkers associated with health benefits.
- Assessment of anti-ageing, firming, moisturising and repairing effects.
- Studies of photoprotection or tanning enhancement.
- Wound healing and tissue repair assays.
- Specific cell models of psoriasis and atopic dermatitis.
Impact and benefits
Generation of robust scientific evidence to support product claims
Studies based on physiologically relevant 2D and 3D in vitro cell models make it possible to generate robust, reproducible and well-characterised data, supported by functional biomarkers and mechanisms of action. This scientific evidence is key to supporting product claims, technical arguments and scientific documentation, in line with the recommendations and scientific frameworks promoted by bodies such as EFSA, the FDA or Cosmetics Europe (formerly COLIPA).
Risk reduction in the development of new ingredients and formulations
Early assessment of the biological and functional effects of products makes it possible to identify potential limitations, lack of efficacy or undesirable effects at the initial stages of development. This reduces technical and scientific uncertainty, minimising risks before moving on to more costly or complex stages of the innovation process.
Acceleration of time-to-market in the early stages of innovation
The use of in vitro models makes it possible to obtain results in shorter timeframes than traditional approaches, facilitating agile, data-driven decision-making. This accelerates concept validation, formulation optimisation and the selection of candidates with greater potential, helping to reduce development and time-to-market.
Optimisation of costs and time compared with traditional approaches
The use of in vitro cell models makes it possible to optimise resources by reducing experimental times, associated costs and the need for more complex testing at early stages. In addition, these approaches align with the principles of the 3Rs (Replacement, Reduction and Refinement), promoting more efficient, ethical and sustainable R&D.
Improvement of the scientific and commercial positioning of products
The generation of data using advanced in vitro models, aligned with international regulatory and scientific trends, strengthens the technical credibility of products among customers, partners and prescribers. This scientific support helps differentiate developments in the market and improve their positioning from both a scientific and commercial perspective.
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