Obten\u00e7\u00e3o de princ\u00edpios ativos (APIs) seguros e sustent\u00e1veis<\/title>\n<meta name=\"description\" content=\"Descobre como a extra\u00e7\u00e3o supercr\u00edtica permite obter princ\u00edpios ativos farmac\u00eauticos puros, seguros e sustent\u00e1veis, sem solventes t\u00f3xicos.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.ainia.com\/pt\/ainia-news\/extracao-supercritica-principio-ativo\/\" \/>\n<meta property=\"og:locale\" content=\"pt_PT\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Obten\u00e7\u00e3o de princ\u00edpios ativos (APIs) seguros e sustent\u00e1veis\" \/>\n<meta property=\"og:description\" content=\"Descobre como a extra\u00e7\u00e3o supercr\u00edtica permite obter princ\u00edpios ativos farmac\u00eauticos puros, seguros e sustent\u00e1veis, sem solventes t\u00f3xicos.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.ainia.com\/pt\/ainia-news\/extracao-supercritica-principio-ativo\/\" \/>\n<meta property=\"og:site_name\" content=\"AINIA\" \/>\n<meta property=\"article:published_time\" content=\"2025-10-31T11:59:45+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2026-04-10T09:14:12+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.ainia.com\/wp-content\/uploads\/2024\/10\/planta-piloto-fluidos-supercriticos-08-2000.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"2000\" \/>\n\t<meta property=\"og:image:height\" content=\"555\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Miguel Garc\u00eda\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Miguel Garc\u00eda\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"4 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.ainia.com\\\/pt\\\/ainia-news\\\/extracao-supercritica-principio-ativo\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.ainia.com\\\/pt\\\/ainia-news\\\/extracao-supercritica-principio-ativo\\\/\"},\"author\":{\"name\":\"Miguel Garc\u00eda\",\"@id\":\"https:\\\/\\\/www.ainia.com\\\/pt\\\/#\\\/schema\\\/person\\\/507fd0bad589bbe3d26889351af2d1c5\"},\"headline\":\"Obten\u00e7\u00e3o de princ\u00edpios ativos (APIs) seguros e sustent\u00e1veis\",\"datePublished\":\"2025-10-31T11:59:45+00:00\",\"dateModified\":\"2026-04-10T09:14:12+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.ainia.com\\\/pt\\\/ainia-news\\\/extracao-supercritica-principio-ativo\\\/\"},\"wordCount\":771,\"publisher\":{\"@id\":\"https:\\\/\\\/www.ainia.com\\\/pt\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/www.ainia.com\\\/pt\\\/ainia-news\\\/extracao-supercritica-principio-ativo\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.ainia.com\\\/wp-content\\\/uploads\\\/2024\\\/10\\\/planta-piloto-fluidos-supercriticos-08-2000.jpg\",\"articleSection\":[\"Inova\u00e7\u00e3o tecnol\u00f3gica\"],\"inLanguage\":\"pt\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.ainia.com\\\/pt\\\/ainia-news\\\/extracao-supercritica-principio-ativo\\\/\",\"url\":\"https:\\\/\\\/www.ainia.com\\\/pt\\\/ainia-news\\\/extracao-supercritica-principio-ativo\\\/\",\"name\":\"Obten\u00e7\u00e3o de princ\u00edpios ativos (APIs) seguros e sustent\u00e1veis\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.ainia.com\\\/pt\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/www.ainia.com\\\/pt\\\/ainia-news\\\/extracao-supercritica-principio-ativo\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/www.ainia.com\\\/pt\\\/ainia-news\\\/extracao-supercritica-principio-ativo\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.ainia.com\\\/wp-content\\\/uploads\\\/2024\\\/10\\\/planta-piloto-fluidos-supercriticos-08-2000.jpg\",\"datePublished\":\"2025-10-31T11:59:45+00:00\",\"dateModified\":\"2026-04-10T09:14:12+00:00\",\"description\":\"Descobre como a extra\u00e7\u00e3o supercr\u00edtica permite obter princ\u00edpios ativos farmac\u00eauticos puros, seguros e sustent\u00e1veis, sem solventes t\u00f3xicos.\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/www.ainia.com\\\/pt\\\/ainia-news\\\/extracao-supercritica-principio-ativo\\\/#breadcrumb\"},\"inLanguage\":\"pt\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/www.ainia.com\\\/pt\\\/ainia-news\\\/extracao-supercritica-principio-ativo\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"pt\",\"@id\":\"https:\\\/\\\/www.ainia.com\\\/pt\\\/ainia-news\\\/extracao-supercritica-principio-ativo\\\/#primaryimage\",\"url\":\"https:\\\/\\\/www.ainia.com\\\/wp-content\\\/uploads\\\/2024\\\/10\\\/planta-piloto-fluidos-supercriticos-08-2000.jpg\",\"contentUrl\":\"https:\\\/\\\/www.ainia.com\\\/wp-content\\\/uploads\\\/2024\\\/10\\\/planta-piloto-fluidos-supercriticos-08-2000.jpg\",\"width\":2000,\"height\":555},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/www.ainia.com\\\/pt\\\/ainia-news\\\/extracao-supercritica-principio-ativo\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Portada\",\"item\":\"https:\\\/\\\/www.ainia.com\\\/pt\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Obten\u00e7\u00e3o de princ\u00edpios ativos (APIs) seguros e sustent\u00e1veis\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/www.ainia.com\\\/pt\\\/#website\",\"url\":\"https:\\\/\\\/www.ainia.com\\\/pt\\\/\",\"name\":\"AINIA\",\"description\":\"AINIA\",\"publisher\":{\"@id\":\"https:\\\/\\\/www.ainia.com\\\/pt\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/www.ainia.com\\\/pt\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"pt\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/www.ainia.com\\\/pt\\\/#organization\",\"name\":\"Ainia\",\"url\":\"https:\\\/\\\/www.ainia.com\\\/pt\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"pt\",\"@id\":\"https:\\\/\\\/www.ainia.com\\\/pt\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/www.ainia.com\\\/wp-content\\\/uploads\\\/2022\\\/01\\\/LOGO-AINIA-simple-alta-resolucion-sin-fondo-1.png\",\"contentUrl\":\"https:\\\/\\\/www.ainia.com\\\/wp-content\\\/uploads\\\/2022\\\/01\\\/LOGO-AINIA-simple-alta-resolucion-sin-fondo-1.png\",\"width\":1000,\"height\":346,\"caption\":\"Ainia\"},\"image\":{\"@id\":\"https:\\\/\\\/www.ainia.com\\\/pt\\\/#\\\/schema\\\/logo\\\/image\\\/\"}},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/www.ainia.com\\\/pt\\\/#\\\/schema\\\/person\\\/507fd0bad589bbe3d26889351af2d1c5\",\"name\":\"Miguel Garc\u00eda\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"pt\",\"@id\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/f782ca5c38b3fa085d9148befee5996da7f3b693bfce7acc8dab43a5e57c9b24?s=96&d=mm&r=g\",\"url\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/f782ca5c38b3fa085d9148befee5996da7f3b693bfce7acc8dab43a5e57c9b24?s=96&d=mm&r=g\",\"contentUrl\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/f782ca5c38b3fa085d9148befee5996da7f3b693bfce7acc8dab43a5e57c9b24?s=96&d=mm&r=g\",\"caption\":\"Miguel Garc\u00eda\"},\"url\":\"https:\\\/\\\/www.ainia.com\\\/pt\\\/ainia-news\\\/author\\\/miguel-garcia\\\/\"}]}<\/script>\n","yoast_head_json":{"title":"Obten\u00e7\u00e3o de princ\u00edpios ativos (APIs) seguros e sustent\u00e1veis","description":"Descobre como a extra\u00e7\u00e3o supercr\u00edtica permite obter princ\u00edpios ativos farmac\u00eauticos puros, seguros e sustent\u00e1veis, sem solventes t\u00f3xicos.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.ainia.com\/pt\/ainia-news\/extracao-supercritica-principio-ativo\/","og_locale":"pt_PT","og_type":"article","og_title":"Obten\u00e7\u00e3o de princ\u00edpios ativos (APIs) seguros e sustent\u00e1veis","og_description":"Descobre como a extra\u00e7\u00e3o supercr\u00edtica permite obter princ\u00edpios ativos farmac\u00eauticos puros, seguros e sustent\u00e1veis, sem solventes t\u00f3xicos.","og_url":"https:\/\/www.ainia.com\/pt\/ainia-news\/extracao-supercritica-principio-ativo\/","og_site_name":"AINIA","article_published_time":"2025-10-31T11:59:45+00:00","article_modified_time":"2026-04-10T09:14:12+00:00","og_image":[{"width":2000,"height":555,"url":"https:\/\/www.ainia.com\/wp-content\/uploads\/2024\/10\/planta-piloto-fluidos-supercriticos-08-2000.jpg","type":"image\/jpeg"}],"author":"Miguel Garc\u00eda","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Miguel Garc\u00eda","Est. reading time":"4 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.ainia.com\/pt\/ainia-news\/extracao-supercritica-principio-ativo\/#article","isPartOf":{"@id":"https:\/\/www.ainia.com\/pt\/ainia-news\/extracao-supercritica-principio-ativo\/"},"author":{"name":"Miguel Garc\u00eda","@id":"https:\/\/www.ainia.com\/pt\/#\/schema\/person\/507fd0bad589bbe3d26889351af2d1c5"},"headline":"Obten\u00e7\u00e3o de princ\u00edpios ativos (APIs) seguros e sustent\u00e1veis","datePublished":"2025-10-31T11:59:45+00:00","dateModified":"2026-04-10T09:14:12+00:00","mainEntityOfPage":{"@id":"https:\/\/www.ainia.com\/pt\/ainia-news\/extracao-supercritica-principio-ativo\/"},"wordCount":771,"publisher":{"@id":"https:\/\/www.ainia.com\/pt\/#organization"},"image":{"@id":"https:\/\/www.ainia.com\/pt\/ainia-news\/extracao-supercritica-principio-ativo\/#primaryimage"},"thumbnailUrl":"https:\/\/www.ainia.com\/wp-content\/uploads\/2024\/10\/planta-piloto-fluidos-supercriticos-08-2000.jpg","articleSection":["Inova\u00e7\u00e3o tecnol\u00f3gica"],"inLanguage":"pt"},{"@type":"WebPage","@id":"https:\/\/www.ainia.com\/pt\/ainia-news\/extracao-supercritica-principio-ativo\/","url":"https:\/\/www.ainia.com\/pt\/ainia-news\/extracao-supercritica-principio-ativo\/","name":"Obten\u00e7\u00e3o de princ\u00edpios ativos (APIs) seguros e sustent\u00e1veis","isPartOf":{"@id":"https:\/\/www.ainia.com\/pt\/#website"},"primaryImageOfPage":{"@id":"https:\/\/www.ainia.com\/pt\/ainia-news\/extracao-supercritica-principio-ativo\/#primaryimage"},"image":{"@id":"https:\/\/www.ainia.com\/pt\/ainia-news\/extracao-supercritica-principio-ativo\/#primaryimage"},"thumbnailUrl":"https:\/\/www.ainia.com\/wp-content\/uploads\/2024\/10\/planta-piloto-fluidos-supercriticos-08-2000.jpg","datePublished":"2025-10-31T11:59:45+00:00","dateModified":"2026-04-10T09:14:12+00:00","description":"Descobre como a extra\u00e7\u00e3o supercr\u00edtica permite obter princ\u00edpios ativos farmac\u00eauticos puros, seguros e sustent\u00e1veis, sem solventes t\u00f3xicos.","breadcrumb":{"@id":"https:\/\/www.ainia.com\/pt\/ainia-news\/extracao-supercritica-principio-ativo\/#breadcrumb"},"inLanguage":"pt","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.ainia.com\/pt\/ainia-news\/extracao-supercritica-principio-ativo\/"]}]},{"@type":"ImageObject","inLanguage":"pt","@id":"https:\/\/www.ainia.com\/pt\/ainia-news\/extracao-supercritica-principio-ativo\/#primaryimage","url":"https:\/\/www.ainia.com\/wp-content\/uploads\/2024\/10\/planta-piloto-fluidos-supercriticos-08-2000.jpg","contentUrl":"https:\/\/www.ainia.com\/wp-content\/uploads\/2024\/10\/planta-piloto-fluidos-supercriticos-08-2000.jpg","width":2000,"height":555},{"@type":"BreadcrumbList","@id":"https:\/\/www.ainia.com\/pt\/ainia-news\/extracao-supercritica-principio-ativo\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Portada","item":"https:\/\/www.ainia.com\/pt\/"},{"@type":"ListItem","position":2,"name":"Obten\u00e7\u00e3o de princ\u00edpios ativos (APIs) seguros e sustent\u00e1veis"}]},{"@type":"WebSite","@id":"https:\/\/www.ainia.com\/pt\/#website","url":"https:\/\/www.ainia.com\/pt\/","name":"AINIA","description":"AINIA","publisher":{"@id":"https:\/\/www.ainia.com\/pt\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.ainia.com\/pt\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"pt"},{"@type":"Organization","@id":"https:\/\/www.ainia.com\/pt\/#organization","name":"Ainia","url":"https:\/\/www.ainia.com\/pt\/","logo":{"@type":"ImageObject","inLanguage":"pt","@id":"https:\/\/www.ainia.com\/pt\/#\/schema\/logo\/image\/","url":"https:\/\/www.ainia.com\/wp-content\/uploads\/2022\/01\/LOGO-AINIA-simple-alta-resolucion-sin-fondo-1.png","contentUrl":"https:\/\/www.ainia.com\/wp-content\/uploads\/2022\/01\/LOGO-AINIA-simple-alta-resolucion-sin-fondo-1.png","width":1000,"height":346,"caption":"Ainia"},"image":{"@id":"https:\/\/www.ainia.com\/pt\/#\/schema\/logo\/image\/"}},{"@type":"Person","@id":"https:\/\/www.ainia.com\/pt\/#\/schema\/person\/507fd0bad589bbe3d26889351af2d1c5","name":"Miguel Garc\u00eda","image":{"@type":"ImageObject","inLanguage":"pt","@id":"https:\/\/secure.gravatar.com\/avatar\/f782ca5c38b3fa085d9148befee5996da7f3b693bfce7acc8dab43a5e57c9b24?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/f782ca5c38b3fa085d9148befee5996da7f3b693bfce7acc8dab43a5e57c9b24?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/f782ca5c38b3fa085d9148befee5996da7f3b693bfce7acc8dab43a5e57c9b24?s=96&d=mm&r=g","caption":"Miguel Garc\u00eda"},"url":"https:\/\/www.ainia.com\/pt\/ainia-news\/author\/miguel-garcia\/"}]}},"_links":{"self":[{"href":"https:\/\/www.ainia.com\/pt\/wp-json\/wp\/v2\/posts\/183707","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.ainia.com\/pt\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.ainia.com\/pt\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.ainia.com\/pt\/wp-json\/wp\/v2\/users\/249"}],"replies":[{"embeddable":true,"href":"https:\/\/www.ainia.com\/pt\/wp-json\/wp\/v2\/comments?post=183707"}],"version-history":[{"count":5,"href":"https:\/\/www.ainia.com\/pt\/wp-json\/wp\/v2\/posts\/183707\/revisions"}],"predecessor-version":[{"id":191452,"href":"https:\/\/www.ainia.com\/pt\/wp-json\/wp\/v2\/posts\/183707\/revisions\/191452"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.ainia.com\/pt\/wp-json\/wp\/v2\/media\/174703"}],"wp:attachment":[{"href":"https:\/\/www.ainia.com\/pt\/wp-json\/wp\/v2\/media?parent=183707"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.ainia.com\/pt\/wp-json\/wp\/v2\/categories?post=183707"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.ainia.com\/pt\/wp-json\/wp\/v2\/tags?post=183707"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}

[vc_row][vc_column][vc_column_text css=\u201d\u201d]<\/span><\/span><\/span><\/span><\/span><\/span>A crescente procura por solu\u00e7\u00f5es mais sustent\u00e1veis e eficientes na ind\u00fastria farmac\u00eautica tem impulsionado a ado\u00e7\u00e3o de tecnologias limpas para a obten\u00e7\u00e3o de <\/span>princ\u00edpios ativos<\/span><\/b>. Uma das mais avan\u00e7adas e vers\u00e1teis \u00e9 a extra\u00e7\u00e3o por fluidos supercr\u00edticos (SFE)<\/a><\/strong>, especialmente com di\u00f3xido de carbono (CO\u2082). Esta t\u00e9cnica permite obter <\/span>princ\u00edpios ativos farmac\u00eauticos<\/span><\/b> com elevada pureza, minimizando o uso de solventes org\u00e2nicos e preservando a integridade de mol\u00e9culas sens\u00edveis.<\/span>\u00a0<\/span><\/p>\n

O papel dos fluidos supercr\u00edticos na produ\u00e7\u00e3o de princ\u00edpios ativos farmac\u00eauticos<\/span><\/b>\u00a0<\/span><\/h2>\nOs fluidos supercr\u00edticos, em particular o <\/span>CO\u2082 supercr\u00edtico<\/span><\/b>, representam uma tecnologia limpa, inovadora e escal\u00e1vel para a extra\u00e7\u00e3o de <\/span>princ\u00edpios ativos farmac\u00eauticos<\/a><\/strong>. As principais vantagens incluem:<\/span>\u00a0<\/span><\/p>\n
\n
O CO\u2082, em estado supercr\u00edtico, combina a difus\u00e3o de um g\u00e1s com o poder de solubiliza\u00e7\u00e3o de um l\u00edquido. A sua solubilidade pode ser ajustada de forma precisa atrav\u00e9s da press\u00e3o e da temperatura.<\/span>\u00a0<\/span><\/li>\n<\/ul>\n
\n
Trata-se de um solvente n\u00e3o t\u00f3xico, n\u00e3o inflam\u00e1vel e totalmente recicl\u00e1vel, eliminando a necessidade de solventes org\u00e2nicos e res\u00edduos perigosos.<\/span>\u00a0<\/span><\/li>\n<\/ul>\n
\n
Opera a temperaturas moderadas e na aus\u00eancia de oxig\u00e9nio, o que permite preservar compostos termossens\u00edveis como vitaminas, antioxidantes e outras subst\u00e2ncias bioativas.<\/span>\u00a0<\/span><\/li>\n<\/ul>\n
\n
Permite extra\u00e7\u00f5es altamente seletivas, ideais para isolar <\/span>princ\u00edpios ativos<\/span><\/b> espec\u00edficos ou fracionar compostos conforme o seu perfil qu\u00edmico.<\/span>\u00a0<\/span><\/li>\n<\/ul>\n
\n
Possibilita a inativa\u00e7\u00e3o microbiol\u00f3gica sem recorrer a calor extremo, algo relevante para mat\u00e9rias-primas que requerem controlo de agentes patog\u00e9nicos.<\/span>\u00a0<\/span><\/li>\n<\/ul>\n
Na plataforma <\/span>ALTEX da AINIA<\/span><\/b>, esta tecnologia \u00e9 aplicada desde escala piloto at\u00e9 escala industrial (20 L \u2013 1.000 L), com certifica\u00e7\u00f5es ECO e GMP. \u00c9 especialmente relevante para <\/span>CMOs e CDMOs<\/span><\/b> que necessitam de solu\u00e7\u00f5es certificadas, robustas e escal\u00e1veis para a produ\u00e7\u00e3o de <\/span>princ\u00edpios ativos farmac\u00eauticos<\/span><\/b>.<\/span>\u00a0<\/span><\/p>\n
Uma tecnologia chave para uma ind\u00fastria farmac\u00eautica mais limpa e competitiva<\/span><\/b>\u00a0<\/span><\/h2>\n
A extra\u00e7\u00e3o com fluidos supercr\u00edticos tornou-se uma <\/span>tecnologia essencial<\/span><\/b> para a produ\u00e7\u00e3o de <\/span>princ\u00edpios ativos farmac\u00eauticos<\/a><\/strong>.<\/strong> A sua capacidade de conjugar efici\u00eancia, sustentabilidade e seguran\u00e7a torna-a uma alternativa vi\u00e1vel aos m\u00e9todos tradicionais, num contexto em que a pureza do produto, o cumprimento regulat\u00f3rio e o respeito pelo ambiente s\u00e3o priorit\u00e1rios.<\/span>\u00a0<\/span><\/p>\n
A sua versatilidade permite ainda aplica\u00e7\u00f5es noutros setores como a alimenta\u00e7\u00e3o, a cosm\u00e9tica e a biomedicina, refor\u00e7ando o seu papel como ferramenta transversal de inova\u00e7\u00e3o industrial. Integrada em processos reais e personalizados, esta tecnologia contribui para uma ind\u00fastria mais sustent\u00e1vel, competitiva e preparada para o futuro.<\/span>\u00a0<\/span><\/p>\n
Outras aplica\u00e7\u00f5es dos fluidos supercr\u00edticos<\/span><\/b>\u00a0<\/span><\/h2>\n
Para al\u00e9m do setor farmac\u00eautico, os <\/span>fluidos supercr\u00edticos<\/span><\/b> est\u00e3o a afirmar-se como uma ferramenta vers\u00e1til noutros setores industriais. Eis algumas aplica\u00e7\u00f5es relevantes:<\/span>\u00a0<\/span><\/p>\n
Valoriza\u00e7\u00e3o de subprodutos agr\u00edcolas\u00a0<\/strong><\/h3>\nA extra\u00e7\u00e3o com CO\u2082 supercr\u00edtico<\/a><\/strong> ou com \u00e1gua subcr\u00edtica permite valorizar res\u00edduos agr\u00edcolas como cascas de cebola, farelo de arroz, cascas de frutos secos ou borras de caf\u00e9, obtendo flavonoides, a\u00e7\u00facares e compostos bioativos com elevado valor funcional.<\/span>\u00a0<\/span><\/p>\n
Ingredientes funcionais para os setores alimentar e cosm\u00e9tico\u00a0<\/strong><\/h3>\n
Al\u00e9m dos <\/span>princ\u00edpios ativos farmac\u00eauticos<\/span><\/b>, os fluidos supercr\u00edticos facilitam a obten\u00e7\u00e3o de extratos naturais puros, utilizados como \u00f3leos essenciais, antioxidantes, pigmentos ou outros <\/span>princ\u00edpios ativos<\/span><\/b> funcionais para formula\u00e7\u00f5es alimentares e cosm\u00e9ticas.<\/span>\u00a0<\/span><\/p>\n
Produ\u00e7\u00e3o de micro e nanopart\u00edculas terap\u00eauticas\u00a0<\/strong><\/h3>\n
Tecnologias inovadoras como <\/span>SAS (Supercritical Anti-Solvent)<\/span><\/b> ou <\/span>DELOS<\/span><\/b> utilizam CO\u2082 supercr\u00edtico para gerar micro\/nanopart\u00edculas, aerog\u00e9is e sistemas de liberta\u00e7\u00e3o controlada. Estas tecnologias aplicam-se em terapias inalat\u00f3rias, administra\u00e7\u00e3o oral ou delivery direcionado de <\/span>princ\u00edpios ativos<\/span><\/b>.<\/span>\u00a0<\/span><\/p>\n
Materiais biom\u00e9dicos e aerog\u00e9is\u00a0<\/strong><\/h3>\n
A secagem supercr\u00edtica com CO\u2082 permite produzir aerog\u00e9is porosos e biocompat\u00edveis a partir de amido, quitosano ou celulose. Estes materiais s\u00e3o indicados para aplica\u00e7\u00f5es biom\u00e9dicas como suportes de regenera\u00e7\u00e3o tecidular, sistemas de liberta\u00e7\u00e3o de f\u00e1rmacos ou pensos m\u00e9dicos.<\/span>\u00a0<\/span><\/p>\n
Qu\u00edmica verde e economia circular\u00a0<\/strong><\/h3>\n
Os fluidos supercr\u00edticos tamb\u00e9m se integram em processos de valoriza\u00e7\u00e3o de res\u00edduos, por exemplo, na extra\u00e7\u00e3o de compostos valiosos de res\u00edduos de constru\u00e7\u00e3o para fabricar aerog\u00e9is isolantes \u2014 reduzindo custos e pegada de carbono at\u00e9 40%.<\/span>\u00a0<\/span><\/p>\n
$\"\"$ <\/p>\n
Financiado pelo programa de\u00a0<\/span>apoios<\/span>\u00a0\u00e0\u00a0<\/span>contrata\u00e7\u00e3o<\/span>\u00a0de\u00a0<\/span>jovens<\/span>\u00a0especializados em\u00a0<\/span>internacionaliza\u00e7\u00e3o<\/span><\/strong><\/em><\/p>\n
$\"\"$ [\/vc_column_text][\/vc_column][\/vc_row]<\/span><\/p>\n<\/div><\/body><\/html>","protected":false},"excerpt":{"rendered":"
[vc_row][vc_column][vc_column_text css=\u201d\u201d]A crescente procura por solu\u00e7\u00f5es mais sustent\u00e1veis e eficientes na ind\u00fastria farmac\u00eautica tem impulsionado a ado\u00e7\u00e3o de tecnologias limpas para a obten\u00e7\u00e3o de princ\u00edpios ativos. Uma das mais avan\u00e7adas e vers\u00e1teis \u00e9 a extra\u00e7\u00e3o por fluidos supercr\u00edticos (SFE), especialmente com di\u00f3xido de carbono (CO\u2082). Esta t\u00e9cnica permite obter princ\u00edpios ativos farmac\u00eauticos com elevada pureza, […]<\/p>\n","protected":false},"author":249,"featured_media":174703,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"categories":[1963],"tags":[],"class_list":["post-183707","post","type-post","status-publish","format-standard","hentry","category-inovacao-tecnologica"],"acf":[],"yoast_head":"\nObten\u00e7\u00e3o de princ\u00edpios ativos (APIs) seguros e sustent\u00e1veis<\/title>\n<meta name=\"description\" content=\"Descobre como a extra\u00e7\u00e3o supercr\u00edtica permite obter princ\u00edpios ativos farmac\u00eauticos puros, seguros e sustent\u00e1veis, sem solventes t\u00f3xicos.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.ainia.com\/pt\/ainia-news\/extracao-supercritica-principio-ativo\/\" \/>\n<meta property=\"og:locale\" content=\"pt_PT\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Obten\u00e7\u00e3o de princ\u00edpios ativos (APIs) seguros e sustent\u00e1veis\" \/>\n<meta property=\"og:description\" content=\"Descobre como a extra\u00e7\u00e3o supercr\u00edtica permite obter princ\u00edpios ativos farmac\u00eauticos puros, seguros e sustent\u00e1veis, sem solventes t\u00f3xicos.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.ainia.com\/pt\/ainia-news\/extracao-supercritica-principio-ativo\/\" \/>\n<meta property=\"og:site_name\" content=\"AINIA\" \/>\n<meta property=\"article:published_time\" content=\"2025-10-31T11:59:45+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2026-04-10T09:14:12+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.ainia.com\/wp-content\/uploads\/2024\/10\/planta-piloto-fluidos-supercriticos-08-2000.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"2000\" \/>\n\t<meta property=\"og:image:height\" content=\"555\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Miguel Garc\u00eda\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Miguel Garc\u00eda\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"4 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.ainia.com\\\/pt\\\/ainia-news\\\/extracao-supercritica-principio-ativo\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.ainia.com\\\/pt\\\/ainia-news\\\/extracao-supercritica-principio-ativo\\\/\"},\"author\":{\"name\":\"Miguel Garc\u00eda\",\"@id\":\"https:\\\/\\\/www.ainia.com\\\/pt\\\/#\\\/schema\\\/person\\\/507fd0bad589bbe3d26889351af2d1c5\"},\"headline\":\"Obten\u00e7\u00e3o de princ\u00edpios ativos (APIs) seguros e sustent\u00e1veis\",\"datePublished\":\"2025-10-31T11:59:45+00:00\",\"dateModified\":\"2026-04-10T09:14:12+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.ainia.com\\\/pt\\\/ainia-news\\\/extracao-supercritica-principio-ativo\\\/\"},\"wordCount\":771,\"publisher\":{\"@id\":\"https:\\\/\\\/www.ainia.com\\\/pt\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/www.ainia.com\\\/pt\\\/ainia-news\\\/extracao-supercritica-principio-ativo\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.ainia.com\\\/wp-content\\\/uploads\\\/2024\\\/10\\\/planta-piloto-fluidos-supercriticos-08-2000.jpg\",\"articleSection\":[\"Inova\u00e7\u00e3o tecnol\u00f3gica\"],\"inLanguage\":\"pt\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.ainia.com\\\/pt\\\/ainia-news\\\/extracao-supercritica-principio-ativo\\\/\",\"url\":\"https:\\\/\\\/www.ainia.com\\\/pt\\\/ainia-news\\\/extracao-supercritica-principio-ativo\\\/\",\"name\":\"Obten\u00e7\u00e3o de princ\u00edpios ativos (APIs) seguros e sustent\u00e1veis\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.ainia.com\\\/pt\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/www.ainia.com\\\/pt\\\/ainia-news\\\/extracao-supercritica-principio-ativo\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/www.ainia.com\\\/pt\\\/ainia-news\\\/extracao-supercritica-principio-ativo\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.ainia.com\\\/wp-content\\\/uploads\\\/2024\\\/10\\\/planta-piloto-fluidos-supercriticos-08-2000.jpg\",\"datePublished\":\"2025-10-31T11:59:45+00:00\",\"dateModified\":\"2026-04-10T09:14:12+00:00\",\"description\":\"Descobre como a extra\u00e7\u00e3o supercr\u00edtica permite obter princ\u00edpios ativos farmac\u00eauticos puros, seguros e sustent\u00e1veis, sem solventes t\u00f3xicos.\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/www.ainia.com\\\/pt\\\/ainia-news\\\/extracao-supercritica-principio-ativo\\\/#breadcrumb\"},\"inLanguage\":\"pt\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/www.ainia.com\\\/pt\\\/ainia-news\\\/extracao-supercritica-principio-ativo\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"pt\",\"@id\":\"https:\\\/\\\/www.ainia.com\\\/pt\\\/ainia-news\\\/extracao-supercritica-principio-ativo\\\/#primaryimage\",\"url\":\"https:\\\/\\\/www.ainia.com\\\/wp-content\\\/uploads\\\/2024\\\/10\\\/planta-piloto-fluidos-supercriticos-08-2000.jpg\",\"contentUrl\":\"https:\\\/\\\/www.ainia.com\\\/wp-content\\\/uploads\\\/2024\\\/10\\\/planta-piloto-fluidos-supercriticos-08-2000.jpg\",\"width\":2000,\"height\":555},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/www.ainia.com\\\/pt\\\/ainia-news\\\/extracao-supercritica-principio-ativo\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Portada\",\"item\":\"https:\\\/\\\/www.ainia.com\\\/pt\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Obten\u00e7\u00e3o de princ\u00edpios ativos (APIs) seguros e sustent\u00e1veis\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/www.ainia.com\\\/pt\\\/#website\",\"url\":\"https:\\\/\\\/www.ainia.com\\\/pt\\\/\",\"name\":\"AINIA\",\"description\":\"AINIA\",\"publisher\":{\"@id\":\"https:\\\/\\\/www.ainia.com\\\/pt\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/www.ainia.com\\\/pt\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"pt\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/www.ainia.com\\\/pt\\\/#organization\",\"name\":\"Ainia\",\"url\":\"https:\\\/\\\/www.ainia.com\\\/pt\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"pt\",\"@id\":\"https:\\\/\\\/www.ainia.com\\\/pt\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/www.ainia.com\\\/wp-content\\\/uploads\\\/2022\\\/01\\\/LOGO-AINIA-simple-alta-resolucion-sin-fondo-1.png\",\"contentUrl\":\"https:\\\/\\\/www.ainia.com\\\/wp-content\\\/uploads\\\/2022\\\/01\\\/LOGO-AINIA-simple-alta-resolucion-sin-fondo-1.png\",\"width\":1000,\"height\":346,\"caption\":\"Ainia\"},\"image\":{\"@id\":\"https:\\\/\\\/www.ainia.com\\\/pt\\\/#\\\/schema\\\/logo\\\/image\\\/\"}},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/www.ainia.com\\\/pt\\\/#\\\/schema\\\/person\\\/507fd0bad589bbe3d26889351af2d1c5\",\"name\":\"Miguel Garc\u00eda\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"pt\",\"@id\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/f782ca5c38b3fa085d9148befee5996da7f3b693bfce7acc8dab43a5e57c9b24?s=96&d=mm&r=g\",\"url\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/f782ca5c38b3fa085d9148befee5996da7f3b693bfce7acc8dab43a5e57c9b24?s=96&d=mm&r=g\",\"contentUrl\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/f782ca5c38b3fa085d9148befee5996da7f3b693bfce7acc8dab43a5e57c9b24?s=96&d=mm&r=g\",\"caption\":\"Miguel Garc\u00eda\"},\"url\":\"https:\\\/\\\/www.ainia.com\\\/pt\\\/ainia-news\\\/author\\\/miguel-garcia\\\/\"}]}<\/script>\n","yoast_head_json":{"title":"Obten\u00e7\u00e3o de princ\u00edpios ativos (APIs) seguros e sustent\u00e1veis","description":"Descobre como a extra\u00e7\u00e3o supercr\u00edtica permite obter princ\u00edpios ativos farmac\u00eauticos puros, seguros e sustent\u00e1veis, sem solventes t\u00f3xicos.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.ainia.com\/pt\/ainia-news\/extracao-supercritica-principio-ativo\/","og_locale":"pt_PT","og_type":"article","og_title":"Obten\u00e7\u00e3o de princ\u00edpios ativos (APIs) seguros e sustent\u00e1veis","og_description":"Descobre como a extra\u00e7\u00e3o supercr\u00edtica permite obter princ\u00edpios ativos farmac\u00eauticos puros, seguros e sustent\u00e1veis, sem solventes t\u00f3xicos.","og_url":"https:\/\/www.ainia.com\/pt\/ainia-news\/extracao-supercritica-principio-ativo\/","og_site_name":"AINIA","article_published_time":"2025-10-31T11:59:45+00:00","article_modified_time":"2026-04-10T09:14:12+00:00","og_image":[{"width":2000,"height":555,"url":"https:\/\/www.ainia.com\/wp-content\/uploads\/2024\/10\/planta-piloto-fluidos-supercriticos-08-2000.jpg","type":"image\/jpeg"}],"author":"Miguel Garc\u00eda","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Miguel Garc\u00eda","Est. reading time":"4 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.ainia.com\/pt\/ainia-news\/extracao-supercritica-principio-ativo\/#article","isPartOf":{"@id":"https:\/\/www.ainia.com\/pt\/ainia-news\/extracao-supercritica-principio-ativo\/"},"author":{"name":"Miguel Garc\u00eda","@id":"https:\/\/www.ainia.com\/pt\/#\/schema\/person\/507fd0bad589bbe3d26889351af2d1c5"},"headline":"Obten\u00e7\u00e3o de princ\u00edpios ativos (APIs) seguros e sustent\u00e1veis","datePublished":"2025-10-31T11:59:45+00:00","dateModified":"2026-04-10T09:14:12+00:00","mainEntityOfPage":{"@id":"https:\/\/www.ainia.com\/pt\/ainia-news\/extracao-supercritica-principio-ativo\/"},"wordCount":771,"publisher":{"@id":"https:\/\/www.ainia.com\/pt\/#organization"},"image":{"@id":"https:\/\/www.ainia.com\/pt\/ainia-news\/extracao-supercritica-principio-ativo\/#primaryimage"},"thumbnailUrl":"https:\/\/www.ainia.com\/wp-content\/uploads\/2024\/10\/planta-piloto-fluidos-supercriticos-08-2000.jpg","articleSection":["Inova\u00e7\u00e3o tecnol\u00f3gica"],"inLanguage":"pt"},{"@type":"WebPage","@id":"https:\/\/www.ainia.com\/pt\/ainia-news\/extracao-supercritica-principio-ativo\/","url":"https:\/\/www.ainia.com\/pt\/ainia-news\/extracao-supercritica-principio-ativo\/","name":"Obten\u00e7\u00e3o de princ\u00edpios ativos (APIs) seguros e sustent\u00e1veis","isPartOf":{"@id":"https:\/\/www.ainia.com\/pt\/#website"},"primaryImageOfPage":{"@id":"https:\/\/www.ainia.com\/pt\/ainia-news\/extracao-supercritica-principio-ativo\/#primaryimage"},"image":{"@id":"https:\/\/www.ainia.com\/pt\/ainia-news\/extracao-supercritica-principio-ativo\/#primaryimage"},"thumbnailUrl":"https:\/\/www.ainia.com\/wp-content\/uploads\/2024\/10\/planta-piloto-fluidos-supercriticos-08-2000.jpg","datePublished":"2025-10-31T11:59:45+00:00","dateModified":"2026-04-10T09:14:12+00:00","description":"Descobre como a extra\u00e7\u00e3o supercr\u00edtica permite obter princ\u00edpios ativos farmac\u00eauticos puros, seguros e sustent\u00e1veis, sem solventes t\u00f3xicos.","breadcrumb":{"@id":"https:\/\/www.ainia.com\/pt\/ainia-news\/extracao-supercritica-principio-ativo\/#breadcrumb"},"inLanguage":"pt","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.ainia.com\/pt\/ainia-news\/extracao-supercritica-principio-ativo\/"]}]},{"@type":"ImageObject","inLanguage":"pt","@id":"https:\/\/www.ainia.com\/pt\/ainia-news\/extracao-supercritica-principio-ativo\/#primaryimage","url":"https:\/\/www.ainia.com\/wp-content\/uploads\/2024\/10\/planta-piloto-fluidos-supercriticos-08-2000.jpg","contentUrl":"https:\/\/www.ainia.com\/wp-content\/uploads\/2024\/10\/planta-piloto-fluidos-supercriticos-08-2000.jpg","width":2000,"height":555},{"@type":"BreadcrumbList","@id":"https:\/\/www.ainia.com\/pt\/ainia-news\/extracao-supercritica-principio-ativo\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Portada","item":"https:\/\/www.ainia.com\/pt\/"},{"@type":"ListItem","position":2,"name":"Obten\u00e7\u00e3o de princ\u00edpios ativos (APIs) seguros e sustent\u00e1veis"}]},{"@type":"WebSite","@id":"https:\/\/www.ainia.com\/pt\/#website","url":"https:\/\/www.ainia.com\/pt\/","name":"AINIA","description":"AINIA","publisher":{"@id":"https:\/\/www.ainia.com\/pt\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.ainia.com\/pt\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"pt"},{"@type":"Organization","@id":"https:\/\/www.ainia.com\/pt\/#organization","name":"Ainia","url":"https:\/\/www.ainia.com\/pt\/","logo":{"@type":"ImageObject","inLanguage":"pt","@id":"https:\/\/www.ainia.com\/pt\/#\/schema\/logo\/image\/","url":"https:\/\/www.ainia.com\/wp-content\/uploads\/2022\/01\/LOGO-AINIA-simple-alta-resolucion-sin-fondo-1.png","contentUrl":"https:\/\/www.ainia.com\/wp-content\/uploads\/2022\/01\/LOGO-AINIA-simple-alta-resolucion-sin-fondo-1.png","width":1000,"height":346,"caption":"Ainia"},"image":{"@id":"https:\/\/www.ainia.com\/pt\/#\/schema\/logo\/image\/"}},{"@type":"Person","@id":"https:\/\/www.ainia.com\/pt\/#\/schema\/person\/507fd0bad589bbe3d26889351af2d1c5","name":"Miguel Garc\u00eda","image":{"@type":"ImageObject","inLanguage":"pt","@id":"https:\/\/secure.gravatar.com\/avatar\/f782ca5c38b3fa085d9148befee5996da7f3b693bfce7acc8dab43a5e57c9b24?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/f782ca5c38b3fa085d9148befee5996da7f3b693bfce7acc8dab43a5e57c9b24?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/f782ca5c38b3fa085d9148befee5996da7f3b693bfce7acc8dab43a5e57c9b24?s=96&d=mm&r=g","caption":"Miguel Garc\u00eda"},"url":"https:\/\/www.ainia.com\/pt\/ainia-news\/author\/miguel-garcia\/"}]}},"_links":{"self":[{"href":"https:\/\/www.ainia.com\/pt\/wp-json\/wp\/v2\/posts\/183707","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.ainia.com\/pt\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.ainia.com\/pt\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.ainia.com\/pt\/wp-json\/wp\/v2\/users\/249"}],"replies":[{"embeddable":true,"href":"https:\/\/www.ainia.com\/pt\/wp-json\/wp\/v2\/comments?post=183707"}],"version-history":[{"count":5,"href":"https:\/\/www.ainia.com\/pt\/wp-json\/wp\/v2\/posts\/183707\/revisions"}],"predecessor-version":[{"id":191452,"href":"https:\/\/www.ainia.com\/pt\/wp-json\/wp\/v2\/posts\/183707\/revisions\/191452"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.ainia.com\/pt\/wp-json\/wp\/v2\/media\/174703"}],"wp:attachment":[{"href":"https:\/\/www.ainia.com\/pt\/wp-json\/wp\/v2\/media?parent=183707"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.ainia.com\/pt\/wp-json\/wp\/v2\/categories?post=183707"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.ainia.com\/pt\/wp-json\/wp\/v2\/tags?post=183707"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}