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Adem\u00e1s, imparto formaci\u00f3n especializada en congresos y jornadas sectoriales, contribuyendo a la divulgaci\u00f3n cient\u00edfica y al avance de la investigaci\u00f3n aplicada.","sameAs":["https:\/\/www.ainia.com\/contactar-lidia-tomas\/","=https:\/\/www.linkedin.com\/public-profile\/settings?lipi=urnlipaged_flagship3_profile_self_edit_contact-infoSUVPYk6QOSvsEj2ZXWSXQ"],"url":"https:\/\/www.ainia.com\/fr\/ainia-news\/author\/lidia-tomas-cobos\/"}]}},"_links":{"self":[{"href":"https:\/\/www.ainia.com\/fr\/wp-json\/wp\/v2\/posts\/181276","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.ainia.com\/fr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.ainia.com\/fr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.ainia.com\/fr\/wp-json\/wp\/v2\/users\/236"}],"replies":[{"embeddable":true,"href":"https:\/\/www.ainia.com\/fr\/wp-json\/wp\/v2\/comments?post=181276"}],"version-history":[{"count":2,"href":"https:\/\/www.ainia.com\/fr\/wp-json\/wp\/v2\/posts\/181276\/revisions"}],"predecessor-version":[{"id":191518,"href":"https:\/\/www.ainia.com\/fr\/wp-json\/wp\/v2\/posts\/181276\/revisions\/191518"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.ainia.com\/fr\/wp-json\/wp\/v2\/media\/181266"}],"wp:attachment":[{"href":"https:\/\/www.ainia.com\/fr\/wp-json\/wp\/v2\/media?parent=181276"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.ainia.com\/fr\/wp-json\/wp\/v2\/categories?post=181276"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.ainia.com\/fr\/wp-json\/wp\/v2\/tags?post=181276"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}

[vc_row][vc_column][vc_column_text]<\/span><\/span>La sant\u00e9 digestive et la nutrition des animaux<\/strong> sont essentielles pour garantir la sant\u00e9 et la productivit\u00e9 dans tout syst\u00e8me de production, car elles pr\u00e9viennent les maladies et am\u00e9liorent la qualit\u00e9 des produits. C\u2019est pourquoi il est indispensable de valider scientifiquement l\u2019effet d\u2019un ingr\u00e9dient sur la sant\u00e9 digestive animale. Il ne suffit pas d\u2019incorporer des ingr\u00e9dients innovants : il est n\u00e9cessaire de conna\u00eetre leur comportement dans le syst\u00e8me digestif de l\u2019animal et de d\u00e9montrer leur fonctionnalit\u00e9 r\u00e9elle.<\/strong><\/a><\/p>\n

Comment fonctionne la digestion des animaux ?<\/strong><\/h2>\n
M\u00eame si le processus digestif varie selon les esp\u00e8ces \u2014 par exemple entre herbivores, carnivores et omnivores, ou entre animaux monogastriques et ruminants \u2014, il suit g\u00e9n\u00e9ralement une s\u00e9quence fonctionnelle commune : ingestion, digestion m\u00e9canique et enzymatique, fermentation, absorption et \u00e9limination.<\/strong><\/p>\n
La dur\u00e9e de la digestion d\u00e9pend du type d\u2019aliment et du syst\u00e8me digestif de chaque esp\u00e8ce, et peut aller de quelques heures \u00e0 plus d\u2019un jour. Le processus se divise en plusieurs phases : orale, gastrique (ou pr\u00e9gastrique chez les ruminants), intestinale et colique.<\/strong><\/p>\n
\n
Tout commence dans la bouche<\/strong>, par l\u2019ingestion des aliments<\/strong>. Chez les ruminants, en plus de la mastication initiale, le processus de rumination, ou r\u00e9gurgitation, est essentiel. Il permet de remastiquer plusieurs fois les aliments pour faciliter leur d\u00e9gradation. Durant cette phase, une grande quantit\u00e9 de salive est produite, ce qui est fondamental pour maintenir un pH ad\u00e9quat dans le rumen et fournir du bicarbonate.<\/li>\n
Les aliments passent ensuite dans le compartiment gastrique<\/strong>, qui chez les ruminants se compose de quatre cavit\u00e9s : le rumen, le r\u00e9ticulum, l\u2019omasum et l\u2019abomasum.<\/li>\n
\u00c0 partir de l\u00e0, le chyme passe dans l\u2019intestin gr\u00eale<\/strong>, o\u00f9 la digestion est compl\u00e9t\u00e9e gr\u00e2ce aux s\u00e9cr\u00e9tions pancr\u00e9atiques et biliaires, et o\u00f9 se produit l\u2019absorption des nutriments<\/strong> (acides amin\u00e9s, glucose, acides gras, vitamines, min\u00e9raux).<\/li>\n
Les r\u00e9sidus non dig\u00e9r\u00e9s ni absorb\u00e9s passent dans le gros intestin<\/strong>, o\u00f9 a lieu une seconde fermentation microbienne<\/strong>, moins intense que dans le rumen, ainsi qu\u2019une r\u00e9absorption de l\u2019eau. Enfin, les d\u00e9chets sont \u00e9limin\u00e9s par le rectum et l\u2019anus sous forme de f\u00e8ces.<\/li>\n<\/ul>\n
\u00c9valuation des ingr\u00e9dients gr\u00e2ce \u00e0 la simulation du processus digestif<\/strong><\/h2>\nGr\u00e2ce \u00e0 la simulation in vitro de la digestion des animaux<\/strong>, il est possible d\u2019\u00e9valuer de mani\u00e8re contr\u00f4l\u00e9e et reproductible la bioaccessibilit\u00e9, la biodisponibilit\u00e9<\/a><\/strong> ainsi que l\u2019efficacit\u00e9 sur la sant\u00e9 digestive animale.<\/strong><\/p>\n
Les essais dynamiques in vitro permettent de reproduire les conditions physiologiques de chaque phase du syst\u00e8me digestif<\/a><\/strong> : orale, gastrique, intestinale et colique. Des param\u00e8tres cl\u00e9s tels que le pH, le temps de transit, la concentration en enzymes digestives et en sels biliaires sont reproduits, en s\u2019adaptant au syst\u00e8me digestif de l\u2019esp\u00e8ce cible.<\/strong><\/p>\n
$\"digestor$ <\/strong><\/h3>\nAvantages et applications pratiques du simulateur digestif in vitro chez les animaux<\/strong><\/h3>\nL\u2019utilisation de mod\u00e8les digestifs in vitro<\/a><\/strong> chez les animaux offre de nombreux avantages dans le cadre de la nutrition animale.<\/p>\n
\n
Tout d\u2019abord, ces mod\u00e8les permettent de r\u00e9duire le recours aux essais in vivo<\/strong> lors des phases initiales de d\u00e9veloppement, en offrant une approche plus \u00e9thique, plus efficace et plus \u00e9conomique<\/strong> pour valider les ingr\u00e9dients fonctionnels.<\/li>\n
De plus, en \u00e9tant des syst\u00e8mes contr\u00f4l\u00e9s et reproductibles, ils facilitent la r\u00e9utilisation<\/strong> des m\u00e9thodologies et des donn\u00e9es exp\u00e9rimentales dans diff\u00e9rents contextes d\u2019\u00e9valuation.<\/li>\n
En optimisant les ressources, en minimisant les d\u00e9chets<\/strong> et en encourageant le d\u00e9veloppement de solutions plus respectueuses du bien-\u00eatre animal et de l\u2019environnement.<\/li>\n<\/ul>\n
Cela s\u2019inscrit dans une strat\u00e9gie de R&D<\/strong> plus durable, align\u00e9e sur les principes des 3R (r\u00e9duire, r\u00e9utiliser et recycler)<\/strong><\/p>\n
Sant\u00e9 digestive animale : que permettent les mod\u00e8les digestifs in vitro ?<\/strong><\/h4>\n
Ces simulations sont particuli\u00e8rement utiles pour :<\/p>\n
\n
\n
\u00c9valuer l\u2019interaction d\u2019un ingr\u00e9dient avec le tractus digestif<\/p>\n<\/li>\n
\n
Analyser la digestibilit\u00e9, la bioaccessibilit\u00e9 et la biodisponibilit\u00e9<\/p>\n<\/li>\n
\n
Suivre le profil de lib\u00e9ration.<\/p>\n<\/li>\n<\/ul>\n
Observer son interaction avec le microbiote intestinal : effet probiotique et pr\u00e9biotique<\/strong><\/h4>\nGr\u00e2ce aux mod\u00e8les digestifs in vitro<\/a><\/strong> chez les animaux, nous pouvons :<\/p>\n
\n
\n
Identifier des compos\u00e9s bioactifs<\/p>\n<\/li>\n
\n
\u00c9tudier les m\u00e9canismes d\u2019action<\/p>\n<\/li>\n
\n
Am\u00e9liorer la formulation d\u2019aliments fonctionnels pour animaux de compagnie ou de rente<\/p>\n<\/li>\n
\n
Valider l\u2019effet biologique de suppl\u00e9ments digestifs ou de modulateurs du microbiome<\/p>\n<\/li>\n
\n
Identifier de nouvelles sources de prot\u00e9ines ou d\u2019ingr\u00e9dients alternatifs pour am\u00e9liorer la sant\u00e9 digestive.[\/vc_column_text][\/vc_column][\/vc_row]<\/p>\n<\/li>\n<\/ul>\n
Financ\u00e9 par le programme d\u2019aides \u00e0 l\u2019embauche de jeunes professionnels sp\u00e9cialis\u00e9s en internationalisation<\/strong><\/em>
\n $\"\"$ <\/p>\n<\/div><\/body><\/html>","protected":false},"excerpt":{"rendered":"
[vc_row][vc_column][vc_column_text]La sant\u00e9 digestive et la nutrition des animaux sont essentielles pour garantir la sant\u00e9 et la productivit\u00e9 dans tout syst\u00e8me de production, car elles pr\u00e9viennent les maladies et am\u00e9liorent la qualit\u00e9 des produits. C\u2019est pourquoi il est indispensable de valider scientifiquement l\u2019effet d\u2019un ingr\u00e9dient sur la sant\u00e9 digestive animale. 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